Inhibitors

Yervoy® (ipilimumab), which targets the CTLA-4 checkpoint molecule on activated immune cells, has been at the vanguard of checkpoint inhibitors, and was approved to treat melanoma in 2011. Patients with melanoma got more…

On Sunday at the European Society of Medical Oncology (ESMO) 2016 Congress, Merck revealed results of two clinical trials that treated lung cancer patients with immunotherapy and could pave the way for its use as a…

Whereas the first portion of ASCO20 focused on cellular immunotherapies, the latter portion provided more insights into established checkpoint inhibitors that target the PD-1/PD-L1 and CTLA-4 pathways. Special attention…