“Lung cancer is the leading cause of cancer death worldwide, and early detection and treatment through screening with low-dose computed tomography has been investigated as a potential means of reducing lung cancer deaths for more than two decades,” said study author Paul Pinsky, from the U.S. National Cancer Institute.
In 2011, the National Lung Screening Trial (NLST) first reported that the risk of lung cancer death in these high-risk patients was 20% lower when screened with LDCT annually for three years, compared with chest X-ray screening.
That trial included more than 53,000 patients across the United States.
The new study — an extended analysis of patients in the NLST who were followed after the 2011 results were published — confirms the original findings, the researchers said.
The follow-up study was published online recently in the Journal of Thoracic Oncology.
The 2011 study found that 320 patients would have to be screened to prevent one death from lung cancer, while the follow-up study found that 303 patients would have to be screened to prevent one lung cancer death.
— Robert Preidt
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SOURCE: International Association for the Study of Lung Cancer, news release, July 1, 2019